Tg(Myh6*/tetO-Slc8a1)BJych
Transgene Detail

Summary

• Symbol: Tg(Myh6*/tetO-Slc8a1)BJych
• Name: transgene insertion B, Joseph Y Cheung
• MGI ID: MGI:5752791
• Synonyms: NCX1
• Transgene: Tg(Myh6*/tetO-Slc8a1)BJych Location: unknown
• Alliance: Tg(Myh6*/tetO-Slc8a1)BJych page

Transgene origin

• Strain of Origin: FVB/N

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(Myh6*/tetO-Slc8a1)BJych expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  rat

  Slc8a1 (29715)

  Slc8a1

  (MGI:107956)

• Mutation details: This transgene contains the rat Slc8a1 gene driven by a modified mouse alpha-myosin heavy chain minimal promoter (Myh6) fused with tetracycline responsive element (TRE or tetO). Founder B carries 11 copies of the transgene. (J:151091)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:151091 Wang J, et al., Induced overexpression of Na+/Ca2+ exchanger transgene: altered myocyte contractility, [Ca2+]i transients, SR Ca2+ contents, and action potential duration. Am J Physiol Heart Circ Physiol. 2009 Aug;297(2):H590-601
• All: 2 reference(s)