Nr1d2^tm1.1Pbrc
Targeted Allele Detail

Summary

• Symbol: Nr1d2^tm1.1Pbrc
• Name: nuclear receptor subfamily 1, group D, member 2; targeted mutation 1.1, Pennington Biomedical Research Center
• MGI ID: MGI:5752902
• Synonyms: Nr1d2^-, Rev-erbbeta^-
• Gene: Nr1d2 Location: Chr14:4230569-4265642 bp, + strand Genetic Position: Chr14, 7.08 cM
• Alliance: Nr1d2^tm1.1Pbrc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:225389
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

Allele Type: Targeted (Null/knockout) Mutations: Insertion, Intragenic deletion Cre-recombination removed the floxed exon 3. (J:225389)

Generation of the Nr1d2^tm1Pbrc and Nr1d2^tm1.1Pbrc alleles

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nr1d2 Mutation: 25 strains or lines available

References

• Original: J:225389 Banerjee S, et al., Pharmacological targeting of the mammalian clock regulates sleep architecture and emotional behaviour. Nat Commun. 2014;5:5759
• All: 4 reference(s)