Lmr28d^CcS16/Dem
QTL Variant Detail

Summary

• QTL variant: Lmr28d^CcS16/Dem
• Name: leishmaniasis resistance 28d; CcS16/Dem
• MGI ID: MGI:5752963
• QTL: Lmr28d Location: Chr2:114123370-114123532 bp Genetic Position: Chr2, Syntenic

Variant origin

• Strain of Specimen: CcS16/Dem

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: Lmr25b (D10Mit103) was detected in interaction with Lmr28d (D2Mit102), p=0.0133. Homozygous STS/A alleles at both loci were associated with higher levels of IL-2. (J:108764)

References

• Original: J:108764 Havelkova H, et al., Genetics of susceptibility to leishmaniasis in mice: four novel loci and functional heterogeneity of gene effects. Genes Immun. 2006 Apr;7(3):220-33
• All: 1 reference(s)