Cox20^em1(IMPC)Tcp
Endonuclease-mediated Allele Detail

Summary

• Symbol: Cox20^em1(IMPC)Tcp
• Name: cytochrome c oxidase assembly protein 20; endonuclease-mediated mutation 1, The Centre for Phenogenomics
• MGI ID: MGI:5754593
• Gene: Cox20 Location: Chr1:178146695-178150258 bp, + strand Genetic Position: Chr1, 83.16 cM, cytoband H3
• Alliance: Cox20^em1(IMPC)Tcp page
• IMPC: Cox20 gene page

Mutation origin

• Strain of Origin: C57BL/6NCrl
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele produced from project TCPR0431 at TCP by injecting Cas9 mRNA and four guide RNAs with the spacer sequences ACTACATTGCTGTGAATTGG, GACTGGTCACTTCATGCTAG, ATATACGCGCACTTGAGACA and CTCGTCTGTTAAACATTCAA. This resulted in a 683-bp deletion on Chr1 from 178321411 to 178322093 and an indel at Chr1: 178322209_178322210_insTAAAC (GRCm38). (J:165963)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 2 strains available Cell Lines: 0 lines available
• Carrying any Cox20 Mutation: 12 strains or lines available

References

• Original: J:165963 Centre for Modeling Human Disease, Alleles produced for the NorCOMM project by the Centre for Modeling Human Disease (Cmhd), Institute of Biomaterials & Biomedical Engineering, University of Toronto. MGI Direct Data Submission. 2010
• All: 4 reference(s)