Sema3f^tm2Atai
Targeted Allele Detail

Summary

• Symbol: Sema3f^tm2Atai
• Name: sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3F; targeted mutation 2, Atsu Aiba
• MGI ID: MGI:5754793
• Synonyms: Sema3F(loxP-neo)
• Gene: Sema3f Location: Chr9:107558699-107587674 bp, - strand Genetic Position: Chr9, 58.91 cM, cytoband F2
• Alliance: Sema3f^tm2Atai page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:159029
• Parent Cell Line: EB3 (ES Cell)
• Strain of Origin: 129P2/OlaHsd

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ cassette was inserted into exon 3. A floxed neomycin resistance cassette was inserted downstream of exon 3. This allele was used to generate Sema3f^tm1Atai. (J:159029)

Expression

In Mice Carrying this Mutation:

2 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Sema3f Mutation: 41 strains or lines available

Notes

ES cells = EB3, derived from E14TG2a. EB3 cells carry one allele of Pou5f1 that has been inactivated via targeted integration of E14TG2a ES cells with an IRESBSDpA selection cassette.

References

• Original: J:159029 Matsuda I, et al., Development of the somatosensory cortex, the cerebellum, and the main olfactory system in Semaphorin 3F knockout mice. Neurosci Res. 2010 Mar;66(3):321-9
• All: 1 reference(s)