Lmr32f^BALB/cHeA
QTL Variant Detail

Summary

• QTL variant: Lmr32f^BALB/cHeA
• Name: leishmaniasis resistance 32f; BALB/cHeA
• MGI ID: MGI:5755069
• QTL: Lmr32f Location: Chr10:99309418-99309657 bp Genetic Position: Chr10, Syntenic

Variant origin

• Strain of Specimen: BALB/cHeA

Variant description

• Allele Type: QTL
• Mutation: Undefined
• Mutation details: Lmr32f was detected in interaction with Lmr22 influencing IL-4 levels. The highest and lowest level of IL-4 was observed in BALB/c and STS/A homozygotes, respectively, at both loci. (J:152405)

Notes

Candidate Genes

J:152405

A potential candidated gene mapping near the Lmr32 QTL (Lmr32a through Lmr32f), which mapped with D10Mit12 and D10Mit46 between 56.0 cM and 63.0 cM on Chromosome 10 of CcS11/Dem in this map study is Ifng, interferon gamma which maps to 67.0 cM. [Table 9.]

References

• Original: J:152405 Kurey I, et al., Distinct genetic control of parasite elimination, dissemination, and disease after Leishmania major infection. Immunogenetics. 2009 Sep;61(9):619-33
• All: 1 reference(s)