Tg(Glp1r-icre)#Fmgb
Transgene Detail

Summary

• Symbol: Tg(Glp1r-icre)#Fmgb
• Name: transgene insertion, Fiona M Gribble
• MGI ID: MGI:5755096
• Synonyms: glp1r-Cre
• Transgene: Tg(Glp1r-icre)#Fmgb Location: unknown
• Alliance: Tg(Glp1r-icre)#Fmgb page

Transgene origin

• Strain of Origin: (C57BL/6 x CBA)F1

Transgene description

• Transgene Type: Transgenic (Recombinase)
• Mutation: Insertion
• Tg(Glp1r-icre)#Fmgb expression driven by 1 gene
  Transgene expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Glp1r (MGI:99571)

• Mutation details: An improved cre recombinase gene (icre) replaced the sequence between the start codon in exon 1 and the stop codon in exon 13 (BAC RP23-408N20). Two founder lines were generated. The pound symbol (#) is used when no line is specified and/or lines are pooled. (J:229150)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Glp1r (mouse) Summary of all recombinase alleles driven by Glp1r. Comparative matrix view of recombinase activities Alliance mouse Glp1r gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

Notes

One line showed sparse expression in the pancreatic islets and was discontinued.

References

• Original: J:229150 Richards P, et al., Identification and characterization of GLP-1 receptor-expressing cells using a new transgenic mouse model. Diabetes. 2014 Apr;63(4):1224-33
• All: 12 reference(s)