Emilin2tm1.2Jhp
Targeted Allele Detail
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Symbol: |
Emilin2tm1.2Jhp |
Name: |
elastin microfibril interfacer 2; targeted mutation 1.2, Jane Hoover-Plow |
MGI ID: |
MGI:5755385 |
Synonyms: |
E2- |
Gene: |
Emilin2 Location: Chr17:71559167-71618551 bp, - strand Genetic Position: Chr17, 41.87 cM
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Alliance: |
Emilin2tm1.2Jhp page
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Germline Transmission: |
Earliest citation of germline transmission:
J:226863
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
Not Specified
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 3. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 3. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 3. Western blot analysis confirmed the absence of protein expression in the blood.
(J:226863)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Emilin2 Mutation: |
55 strains or lines available
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Original: |
J:226863 Huang M, et al., EMILIN2 regulates platelet activation, thrombus formation, and clot retraction. PLoS One. 2015;10(2):e0115284 |
All: |
1 reference(s) |
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