Ppp1r12a^em1Sfsh
Endonuclease-mediated Allele Detail

Summary

• Symbol: Ppp1r12a^em1Sfsh
• Name: protein phosphatase 1, regulatory subunit 12A; endonuclease-mediated mutation 1, Steven A Fisher
• MGI ID: MGI:5755518
• Synonyms: Mypt1 E24 flox
• Gene: Ppp1r12a Location: Chr10:107997913-108115846 bp, + strand Genetic Position: Chr10, 56.33 cM, cytoband C
• Alliance: Ppp1r12a^em1Sfsh page

Mutation origin

• Strain of Origin: C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Conditional ready)
• Mutation: Insertion
• Mutation details: Zinc finger endonuclease technology introduced loxP sites 300 bp on either side of exon 24, which encodes the regulatory subunit. (J:230106)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Ppp1r12a Mutation: 62 strains or lines available

References

• Original: J:230106 Reho JJ, et al., Neural programming of mesenteric and renal arteries. Am J Physiol Heart Circ Physiol. 2014 Aug 15;307(4):H563-73
• All: 4 reference(s)