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Pitx2tm1b(EUCOMM)Wtsi
Targeted Allele Detail
Summary
Symbol: Pitx2tm1b(EUCOMM)Wtsi
Name: paired-like homeodomain transcription factor 2; targeted mutation 1b, Wellcome Trust Sanger Institute
MGI ID: MGI:5760000
Gene: Pitx2  Location: Chr3:128993527-129013240 bp, + strand  Genetic Position: Chr3, 57.84 cM
Alliance: Pitx2tm1b(EUCOMM)Wtsi page
IMPC: Pitx2 gene page
Mutation
origin
Mutant Cell Line:  EPD0688_3_A07
Germline Transmission:  Earliest citation of germline transmission: J:204739
Parent Cell Line:  JM8A3.N1 (ES Cell)
Strain of Origin:  C57BL/6N-Atm1Brd
Project Collection: EUCOMM
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Intragenic deletion     Vector: L1L2_Bact_P
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 12 assay results
In Structures Affected by this Mutation: 5 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 1 strain available      Cell Lines: 0 lines available
Carrying any Pitx2 Mutation:  39 strains or lines available
References
Original:  J:204739 International Knockout Mouse Consortium, MGI download of modified allele data from IKMC and creation of new knockout alleles. Database Download. 2014-2023;
All:  4 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
12/10/2024
MGI 6.24
The Jackson Laboratory