Tg(CMV-APPL2)1Smoc
Transgene Detail

Summary

• Symbol: Tg(CMV-APPL2)1Smoc
• Name: transgene insertion 1, Shanghai Model Organisms Center
• MGI ID: MGI:5762688
• Synonyms: APPL2 Tg, Tg(CMV-APPL2)#Srcmo
• Transgene: Tg(CMV-APPL2)1Smoc Location: unknown
• Alliance: Tg(CMV-APPL2)1Smoc page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(CMV-APPL2)1Smoc expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  APPL2 (55198)

  Appl2

  (MGI:2384914)

• Mutation details: The CMV immediate early enhancer with a beta-actin minimal promoter drives ubiquitous expression of the human cDNA with a 5' FLAG tag. The pound symbol (#) is used when no lines is specified and/or lines are pooled. (J:230004)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:230004 Cheng KK, et al., The adaptor protein APPL2 inhibits insulin-stimulated glucose uptake by interacting with TBC1D1 in skeletal muscle. Diabetes. 2014 Nov;63(11):3748-58
• All: 3 reference(s)