Riox1^tm1Qch
Targeted Allele Detail

Summary

• Symbol: Riox1^tm1Qch
• Name: ribosomal oxygenase 1; targeted mutation 1, Qin Chen
• MGI ID: MGI:5762848
• Synonyms: NO66^f, NO66flox
• Gene: Riox1 Location: Chr12:83997382-83999725 bp, + strand Genetic Position: Chr12, 38.97 cM, cytoband D3
• Alliance: Riox1^tm1Qch page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224562
• Parent Cell Line: G4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NCrl)F1

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted upstream of the single coding exon. An additional loxP site was inserted downstream of the single coding exon. (J:224562)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Riox1 Mutation: 17 strains or lines available

References

• Original: J:224562 Chen Q, et al., Mesenchymal Deletion of Histone Demethylase NO66 in Mice Promotes Bone Formation. J Bone Miner Res. 2015 Sep;30(9):1608-17
• All: 2 reference(s)