Mir188^em1Xhl
Endonuclease-mediated Allele Detail

Summary

• Symbol: Mir188^em1Xhl
• Name: microRNA 188; endonuclease-mediated mutation 1, Xiang-Hang Luo
• MGI ID: MGI:5763032
• Gene: Mir188 Location: ChrX:7114228-7114295 bp, - strand Genetic Position: ChrX, 3.25 cM
• Alliance: Mir188^em1Xhl page

Mutation origin

• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: TALEN technology was used to knock-out the sequence surrounding and partially overlapping with the microRNA. (J:222099)

Expression

In Structures Affected by this Mutation:

2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Mir188 Mutation: 2 strains or lines available

References

• Original: J:222099 Li CJ, et al., MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation. J Clin Invest. 2015 Apr;125(4):1509-22
• All: 2 reference(s)