Rhox^tm1.1Wilk
Targeted Allele Detail

Summary

• Symbol: Rhox^tm1.1Wilk
• Name: reproductive homeobox cluster; targeted mutation 1.1, Miles F Wilkinson
• MGI ID: MGI:5763218
• Synonyms: Rhox-c-KO
• Gene: Rhox Location: unknown Genetic Position: ChrX, Syntenic

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229199
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutation: Intergenic deletion
• Rhox^tm1.1Wilk involves 50 genes/genome features (Rhox1, Rhox2a, Rhox3a ...) View all
• Mutation details: A loxP sites were inserted upstream of Rhox1 and into the second intron of Rhox13. Cre-mediated recombination removes the entire cluster. (J:229199)

Expression

In Structures Affected by this Mutation:

3 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rhox Mutation: 1 strain or line available

References

• Original: J:229199 Song HW, et al., shRNA off-target effects in vivo: impaired endogenous siRNA expression and spermatogenic defects. PLoS One. 2015;10(3):e0118549
• All: 3 reference(s)