Tg(Fabp4-Phb*Y114F)#Smis
Transgene Detail

Summary

• Symbol: Tg(Fabp4-Phb*Y114F)#Smis
• Name: transgene insertion, Suresh Mishra
• MGI ID: MGI:5763309
• Synonyms: m-Mito-Ob
• Transgene: Tg(Fabp4-Phb*Y114F)#Smis Location: unknown
• Alliance: Tg(Fabp4-Phb*Y114F)#Smis page

Transgene origin

• Strain of Origin: Not Specified

Transgene description

• Transgene Type: Transgenic (Inserted expressed sequence)
• Mutation: Insertion
• Tg(Fabp4-Phb*Y114F)#Smis expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Phb

• Mutation details: The full-length prohibitin cDNA with a substitution of tyrosine-114 by phenylalanine (Y114F) is under the control of the adipocyte protein-2 promoter. The pound symbol (#) is used when line is not specified and/or lines are pooled. (J:227976)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:227976 Ande SR, et al., Expression of a mutant prohibitin from the aP2 gene promoter leads to obesity-linked tumor development in insulin resistance-dependent manner. Oncogene. 2016 Aug 25;35(34):4459-70
• All: 2 reference(s)