Il19^tm2Vlcg
Targeted Allele Detail

Summary

• Symbol: Il19^tm2Vlcg
• Name: interleukin 19; targeted mutation 2, Velocigene
• MGI ID: MGI:5763407
• Gene: Il19 Location: Chr1:130860393-130867852 bp, - strand Genetic Position: Chr1, 56.89 cM
• Alliance: Il19^tm2Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:230642
• Parent Cell Line: F1H4 (ES Cell)
• Strain of Origin: (129S6/SvEvTac x C57BL/6NTac)F1

Mutation description

• Allele Type: Targeted (Null/knockout, Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: The pZEN6 cassette containing a reporter lacZ gene in tandem with a floxed neomycin resistance cassette was used to generate this knock-out allele. (J:230642)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Il19 Mutation: 21 strains or lines available

References

• Original: J:230642 Azuma YT, et al., Interleukin-19 protects mice from innate-mediated colonic inflammation. Inflamm Bowel Dis. 2010 Jun;16(6):1017-28
• All: 6 reference(s)