Psl6^C57BL/6
QTL Variant Detail

Summary

• QTL variant: Psl6^C57BL/6
• Name: promotion susceptibility QTL 6; C57BL/6
• MGI ID: MGI:5767240
• QTL: Psl6 Location: Chr9:65041191-95522808 bp Genetic Position: Chr9, Syntenic

Variant origin

• Strain of Specimen: C57BL/6

Variant description

• Allele Type: QTL
• Inheritance: Not Specified

Notes

Mapping and Phenotype information for this QTL, its variants and associated markers

J:166052

Mapping of tumor promotion susceptibility was studied in congenic mouse strains to identify QTL segregating the phenotype. C57BL/6 Psl1A^DBA and three subcongenic strains were informative in mapping Psl5(Psl1.1) to a region of mouse Chromsoome 9 between D9Mit112 and D9Mit200 and Psl6 (Psl1.2) between D9Mit316 and D9Mit76. Authors suggest Gsta4 as a candidate gene for Psl6.

References

• Original: J:166052 Abel EL, et al., Evidence that Gsta4 modifies susceptibility to skin tumor development in mice and humans. J Natl Cancer Inst. 2010 Nov 3;102(21):1663-75
• All: 1 reference(s)