Mir125a^tm1Smoc
Targeted Allele Detail

Summary

• Symbol: Mir125a^tm1Smoc
• Name: microRNA 125a; targeted mutation 1, Shanghai Model Organisms Center
• MGI ID: MGI:5770229
• Synonyms: Mir125a^tm1Srcmo
• Gene: Mir125a Location: Chr17:18051074-18051141 bp, + strand Genetic Position: Chr17, 10.5 cM
• Alliance: Mir125a^tm1Smoc page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:224880
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• An FRT-flanked neomycin resistance cassette with a 5' loxP site replaced the microRNA sequence. (J:224880)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Mir125a Mutation: 4 strains or lines available

References

• Original: J:224880 Pan W, et al., MiR-125a targets effector programs to stabilize Treg-mediated immune homeostasis. Nat Commun. 2015;6:7096
• All: 2 reference(s)