Tmem203^tm1.1Roml
Targeted Allele Detail

Summary

• Symbol: Tmem203^tm1.1Roml
• Name: transmembrane protein 203; targeted mutation 1.1, Mark A Labow
• MGI ID: MGI:5770432
• Synonyms: Tmem203^deltaATG
• Gene: Tmem203 Location: Chr2:25145451-25146304 bp, + strand Genetic Position: Chr2, 17.11 cM
• Alliance: Tmem203^tm1.1Roml page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:222925
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-flanked neomycin resistance cassette replaced the translation initiation site and 44 nucleotide of the 5' UTR. Flp-mediated recombination removed the selection cassette. (J:222925)

Expression

In Mice Carrying this Mutation:	1 RNA-Seq or microarray experiment(s)
In Structures Affected by this Mutation:	4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Tmem203 Mutation: 11 strains or lines available

References

• Original: J:222925 Shambharkar PB, et al., TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis. PLoS One. 2015;10(5):e0127480
• All: 1 reference(s)