About   Help   FAQ
Ffar3tm2.1Soff
Targeted Allele Detail
Summary
Symbol: Ffar3tm2.1Soff
Name: free fatty acid receptor 3; targeted mutation 2.1, Stefan Offermanns
MGI ID: MGI:5770448
Gene: Ffar3  Location: Chr7:30553755-30555603 bp, - strand  Genetic Position: Chr7, 19.25 cM
Alliance: Ffar3tm2.1Soff page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:227939
Parent Cell Line:  v6.5 (ES Cell)
Strain of Origin:  (C57BL/6 x 129S4/SvJae)F1
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutations:    Insertion, Intragenic deletion
 
Mutation detailsA floxed neomycin resistance cassette replaced the coding exon. Cre-mediated recombination removed the selection cassette and left a loxP site. (J:227939)
Phenotypes
Loading...
View phenotypes and curated references for all genotypes (concatenated display).
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Ffar3 Mutation:  18 strains or lines available
Notes
This allele was generated in ES cells containing Ffar2tm2Soff.
References
Original:  J:227939 Tang C, et al., Loss of FFA2 and FFA3 increases insulin secretion and improves glucose tolerance in type 2 diabetes. Nat Med. 2015 Feb;21(2):173-7
All:  1 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
12/10/2024
MGI 6.24
The Jackson Laboratory