Nabp2^tm1.1Schg
Targeted Allele Detail

Summary

• Symbol: Nabp2^tm1.1Schg
• Name: nucleic acid binding protein 2; targeted mutation 1.1, Sandy Chang
• MGI ID: MGI:5770469
• Synonyms: mSSB1^delta
• Gene: Nabp2 Location: Chr10:128237264-128247361 bp, - strand Genetic Position: Chr10, 76.55 cM, cytoband D3
• Alliance: Nabp2^tm1.1Schg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228558
• Parent Cell Line: AB2.1 (ES Cell)
• Strain of Origin: 129S7/SvEvBrd-Hprt1^b-m2

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT-fanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 2. An additional loxP site was inserted downstream of exon 6. Cre-mediated recombination removed the selection cassette and exons 2 through 6. (J:228558)

Expression

In Mice Carrying this Mutation:	4 assay results
In Structures Affected by this Mutation:	1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Nabp2 Mutation: 16 strains or lines available

References

• Original: J:228558 Gu P, et al., Single strand DNA binding proteins 1 and 2 protect newly replicated telomeres. Cell Res. 2013 May;23(5):705-19
• All: 1 reference(s)