Lbx1^tm2(flpo)Gld
Targeted Allele Detail

Summary

• Symbol: Lbx1^tm2(flpo)Gld
• Name: ladybird homeobox 1; targeted mutation 2, Martyn Goulding
• MGI ID: MGI:5770780
• Synonyms: Lbx1^FlpO
• Gene: Lbx1 Location: Chr19:45221123-45224251 bp, - strand Genetic Position: Chr19, 38.61 cM, cytoband D
• Alliance: Lbx1^tm2(flpo)Gld page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:226610
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Lbx1^tm2(flpo)Gld expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Lbx1 (MGI:104867)

• A FlpO-floxed PGK-Neo cassette was inserted in-frame at amino acid 62 via homologous recombination. (J:226610)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Lbx1 (mouse) Summary of all recombinase alleles driven by Lbx1. Alliance mouse Lbx1 gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Lbx1 Mutation: 13 strains or lines available

References

• Original: J:226610 Bourane S, et al., Gate control of mechanical itch by a subpopulation of spinal cord interneurons. Science. 2015 Oct 30;350(6260):550-4
• All: 18 reference(s)