Tg(CAG-TRIM29)ADims
Transgene Detail

Summary

• Symbol: Tg(CAG-TRIM29)ADims
• Name: transgene insertion A, Diane M Simeone
• MGI ID: MGI:5770788
• Synonyms: CAG-ATDC
• Transgene: Tg(CAG-TRIM29)ADims Location: unknown
• Alliance: Tg(CAG-TRIM29)ADims page

Transgene origin

• Strain of Origin: FVB/NJ

Transgene description

• Transgene Type: Transgenic (Humanized sequence, Inserted expressed sequence)
• Mutation: Insertion
• Tg(CAG-TRIM29)ADims expresses 1 gene
  Transgene expresses:
  

  Organism

  Expressed Gene

  Homolog in Mouse

  Note

  human

  TRIM29 (23650)

  Trim29

  (MGI:1919419)

• Mutation details: The full-length human ataxia-telangiectasia group D complementing (TRIM29 or ATDC) cDNA with a FLAG tag at the 5' end is under the control of the CMV enhancer and the chicken beta-actin promoter (CAG). Three founder lines were established; A, B, and C. Line A carries 6 copies of the transgene. (J:226764)

Disease models

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available

References

• Original: J:226764 Palmbos PL, et al., ATDC/TRIM29 Drives Invasive Bladder Cancer Formation through miRNA-Mediated and Epigenetic Mechanisms. Cancer Res. 2015 Dec 1;75(23):5155-66
• All: 1 reference(s)