Gt(ROSA)26Sor^{tm1(en/Cdx1,-EGFP)Npln}
Targeted Allele Detail

Summary

• Symbol: Gt(ROSA)26Sor^{tm1(en/Cdx1,-EGFP)Npln}
• Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Nicolas Pilon
• MGI ID: MGI:5774458
• Synonyms: R26R^EnRCdx1
• Gene: Gt(ROSA)26Sor Location: Chr6:113044389-113054205 bp, - strand Genetic Position: Chr6, 52.73 cM
• Alliance: Gt(ROSA)26Sor^{tm1(en/Cdx1,-EGFP)Npln} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231654
• Parent Cell Line: R1 (ES Cell)
• Strain of Origin: (129X1/SvJ x 129S1/Sv)F1-Kitl⁺

Mutation description

• Allele Type: Targeted (Conditional ready, Inserted expressed sequence, Reporter)
• Mutation: Insertion
• Gt(ROSA)26Sor^{tm1(en/Cdx1,-EGFP)Npln} expresses 1 gene
  Knock-in expresses:
  

  Organism	Expressed Gene	Note
  Not Specified	Cdx1

• Mutation details: A floxed PGK-neo cassette, a FLAG-tagged fusion protein consisting of the repressor domain of Drosophila engrailed fused to the Cdx1 homeodomain, and IRES-EGFP were inserted into the Gt(ROSA)26Sor locus. (J:231654)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Gt(ROSA)26Sor Mutation: 993 strains or lines available

References

• Original: J:231654 Sanchez-Ferras O, et al., A direct role for murine Cdx proteins in the trunk neural crest gene regulatory network. Development. 2016 Apr 15;143(8):1363-74
• All: 1 reference(s)