Ltbp1^tm1Vlcg
Targeted Allele Detail

Summary

• Symbol: Ltbp1^tm1Vlcg
• Name: latent transforming growth factor beta binding protein 1; targeted mutation 1, Velocigene
• MGI ID: MGI:5774718
• Synonyms: Ltbp1L^lz
• Gene: Ltbp1 Location: Chr17:75312563-75699507 bp, + strand Genetic Position: Chr17, 46.24 cM, cytoband E3
• Alliance: Ltbp1^tm1Vlcg page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:228706
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: 129S/SvEv x C57BL/6

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Most of exon 2 was replaced with a lacZ and neomycin resistance gene cassette. (J:228706)

Expression

In Mice Carrying this Mutation:

95 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ltbp1 Mutation: 115 strains or lines available

References

• Original: J:228706 Chandramouli A, et al., Ltbp1L is focally induced in embryonic mammary mesenchyme, demarcates the ductal luminal lineage and is upregulated during involution. Breast Cancer Res. 2013;15(6):R111
• All: 1 reference(s)