Rac2^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rac2^M2Btlr
• Name: Rac family small GTPase 2; mutation 2, Bruce Beutler
• MGI ID: MGI:5775009
• Synonyms: Big_bend
• Gene: Rac2 Location: Chr15:78443369-78456983 bp, - strand Genetic Position: Chr15, 37.57 cM
• Alliance: Rac2^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to C transition at base pair 78,565,945 (v38) on chromosome 15, or base pair 6,839 in the GenBank genomic region NC_000081. The mutation corresponds to residue 332 in the mRNA sequence NM_009008 within exon 3 of 7 total exons. The mutation results in an aspartic acid (D) to alanine (A) substitution at position 65 (D65A). (J:231801)
• Inheritance: Semidominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rac2 Mutation: 17 strains or lines available

References

• Original: J:231801 Zeng M, et al., Mutagenetix entry for Big_bend. MGI Direct Data Submission. 2016
• All: 1 reference(s)