Rab27a^m3Btlr
Chemically induced Allele Detail

Summary

• Symbol: Rab27a^m3Btlr
• Name: RAB27A, member RAS oncogene family; mutation 3, Bruce Beutler
• MGI ID: MGI:5775010
• Synonyms: ivan
• Gene: Rab27a Location: Chr9:72952136-73004911 bp, + strand Genetic Position: Chr9, 40.08 cM
• Alliance: Rab27a^m3Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to C transition at base pair 73,075,544 (v38) on chromosome 9, or base pair 30,735 in the GenBank genomic region NC_000075. The mutation corresponds to residue 503 in the mRNA sequence NM_001301230 (isoform 1) within exon 3 of 7 total exons, residue 354 in the mRNA sequence NM_023635 (isoform 2) within exon 2 of 6 total exons, and residue 396 in the mRNA sequence NM_001301232 (isoform 3) within exon 2 of 6 total exons. The mutation results in an isoleucine (I) to leucine (L) substitution at position 44 (I44L). (J:231802)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rab27a Mutation: 146 strains or lines available

References

• Original: J:231802 Reyna C, et al., Mutagenetix entry for ivan. MGI Direct Data Submission. 2016
• All: 1 reference(s)