Summary |
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Variant origin |
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Variant description |
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Notes |
Mapping and Phenotype information for this QTL, its variants and associated markersJ:163117Linkage analysis was performed on a mapping population of 252 male and female (ILS x ISS) RI mice (LXS, 63 strains, 4 mice/strain) to identify one genomic locus related to sensorineural hearing loss. Mice were genotyped at 11,000 SNP markers. QTL Snhl1 maps to 54.0 - 60.0 Mb on Chromosome 10 with a peak LOD score of 15.8. ISS-derived alleles are reported to be associated with the sensorineural hearing loss phenotype. Protein-coding gene Cdh23 is suggested as the most likely candidate gene. |
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References |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 08/21/2024 MGI 6.24 |
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