Glp1r^{tm1.1(cre)Lbrl}
Targeted Allele Detail

Summary

• Symbol: Glp1r^{tm1.1(cre)Lbrl}
• Name: glucagon-like peptide 1 receptor; targeted mutation 1.1, Stephen Liberles
• MGI ID: MGI:5776617
• Synonyms: Glp1r-ires-Cre
• Gene: Glp1r Location: Chr17:31120841-31155484 bp, + strand Genetic Position: Chr17, 15.8 cM
• Alliance: Glp1r^{tm1.1(cre)Lbrl} page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232319
• Parent Cell Line: W4 (ES Cell)
• Strain of Origin: 129S6/SvEvTac

Mutation description

• Allele Type: Targeted (Recombinase)
• Mutation: Insertion
• Glp1r^{tm1.1(cre)Lbrl} expression driven by 1 gene
  Knock-in expression driven by:
  

  Organism	Driver Gene	Note
  mouse	Glp1r (MGI:99571)

• Mutation details: A cassette encoding IRES, Cre recombinase, and an FRT-flanked neomycin selection cassette is inserted into the mouse Glp1r locus 3 base pairs downstream of the coding sequence stop codon. (J:232319)

Recombinase activity

Activity:	Tissue activity of this recombinase allele
Driver:	Glp1r (mouse) Summary of all recombinase alleles driven by Glp1r. Comparative matrix view of recombinase activities Alliance mouse Glp1r gene page

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Glp1r Mutation: 49 strains or lines available

References

• Original: J:232319 Williams EK, et al., Sensory Neurons that Detect Stretch and Nutrients in the Digestive System. Cell. 2016 Jun 30;166(1):209-21
• All: 19 reference(s)