Rasal3^tm1.1Fuj
Targeted Allele Detail

Summary

• Symbol: Rasal3^tm1.1Fuj
• Name: RAS protein activator like 3; targeted mutation 1.1, Masahiro Fujii
• MGI ID: MGI:5776708
• Gene: Rasal3 Location: Chr17:32609633-32622557 bp, - strand Genetic Position: Chr17, 17.55 cM
• Alliance: Rasal3^tm1.1Fuj page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:229641
• Parent Cell Line: RENKA (ES Cell)
• Strain of Origin: C57BL/6N

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 3' loxP site was inserted downstream of exon 4. Cre-mediated recombination removed exons 2 through 4 and the selection cassette. (J:229641)

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Rasal3 Mutation: 44 strains or lines available

References

• Original: J:229641 Saito S, et al., RASAL3, a novel hematopoietic RasGAP protein, regulates the number and functions of NKT cells. Eur J Immunol. 2015 May;45(5):1512-23
• All: 2 reference(s)