Pik3c2g^tm1Ehi
Targeted Allele Detail

Summary

• Symbol: Pik3c2g^tm1Ehi
• Name: phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; targeted mutation 1, Emilio Hirsch
• MGI ID: MGI:5779504
• Synonyms: Pik3c2g^lacZ
• Gene: Pik3c2g Location: Chr6:139591070-139915010 bp, + strand Genetic Position: Chr6, 69.7 cM
• Alliance: Pik3c2g^tm1Ehi page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:223018
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Reporter)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A lacZ and floxed neomycin resistance cassette replaced most of exon 1. RT-PCR confirmed the absence of protein expression in the liver. (J:223018)

Expression

In Structures Affected by this Mutation:

4 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pik3c2g Mutation: 77 strains or lines available

References

• Original: J:223018 Braccini L, et al., PI3K-C2gamma is a Rab5 effector selectively controlling endosomal Akt2 activation downstream of insulin signalling. Nat Commun. 2015;6:7400
• All: 1 reference(s)