Tg(tetO/CMV-Pmp22)JP18Clh
Transgene Detail

Summary

• Symbol: Tg(tetO/CMV-Pmp22)JP18Clh
• Name: transgene insertion JP18, Clare Huxley
• MGI ID: MGI:5779548
• Synonyms: JP18, TgN(PMP22)JP18Clh
• Transgene: Tg(tetO/CMV-Pmp22)JP18Clh Location: unknown
• Alliance: Tg(tetO/CMV-Pmp22)JP18Clh page

Transgene origin

• Strain of Origin: (C57BL/6J x CBA/Ca)F1

Transgene description

• Transgene Type: Transgenic (Inducible, Inserted expressed sequence)
• Inducer: doxycycline/tetracycline
• Mutation: Insertion
• Tg(tetO/CMV-Pmp22)JP18Clh expresses 1 gene
  Transgene expresses:
  

  Organism	Expressed Gene	Note
  mouse	Pmp22 (MGI:97631)

• Mutation details: The mouse Pmp22 cDNA is under the control of the tetracycline-regulatable promoter hCMV*-1 containing sequences from the human cytomegalovirus ie1/ie2 promoter and seven upstream tet operator sites. (J:69545)

Disease models

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available

References

• Original: J:69545 Perea J, et al., Induced myelination and demyelination in a conditional mouse model of Charcot-Marie-Tooth disease type 1A. Hum Mol Genet. 2001 May 1;10(10):1007-18
• All: 1 reference(s)