Cerkl^tm1.1Npa
Targeted Allele Detail

Summary

• Symbol: Cerkl^tm1.1Npa
• Name: ceramide kinase-like; targeted mutation 1.1, Novartis Pharma AG
• MGI ID: MGI:5779908
• Synonyms: C-CERKL^TM2NPA
• Gene: Cerkl Location: Chr2:79162835-79259332 bp, - strand Genetic Position: Chr2, 47.43 cM
• Alliance: Cerkl^tm1.1Npa page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:137892
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: BALB/c

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: A loxP site was inserted upstream of exon 5. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 5. Cre-mediated recombination removed exon 5. (J:137892)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Cerkl Mutation: 29 strains or lines available

References

• Original: J:137892 Graf C, et al., Wild-type levels of ceramide and ceramide-1-phosphate in the retina of ceramide kinase-like-deficient mice. Biochem Biophys Res Commun. 2008 Aug 15;373(1):159-63
• All: 1 reference(s)