Dhps^tm1Itl
Targeted Allele Detail

Summary

• Symbol: Dhps^tm1Itl
• Name: deoxyhypusine synthase; targeted mutation 1, inGenious Targeting Laboratory
• MGI ID: MGI:5780995
• Gene: Dhps Location: Chr8:85798386-85801791 bp, + strand Genetic Position: Chr8, 41.55 cM
• Alliance: Dhps^tm1Itl page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:232390
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: An FRT- and loxP- flanked neomycin resistance cassette replaced exons 1 through 7. This allele is not expected to affect Wdr83 within exon 9 on the reverse strand. (J:232390)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dhps Mutation: 21 strains or lines available

References

• Original: J:232390 Templin AT, et al., Deoxyhypusine synthase haploinsufficiency attenuates acute cytokine signaling. Cell Cycle. 2011 Apr 1;10(7):1043-9
• All: 1 reference(s)