Elk3tm1.2Ics
Targeted Allele Detail
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Symbol: |
Elk3tm1.2Ics |
Name: |
ELK3, member of ETS oncogene family; targeted mutation 1.2, Mouse Clinical Institute |
MGI ID: |
MGI:5781314 |
Synonyms: |
Elk3- |
Gene: |
Elk3 Location: Chr10:93083276-93146997 bp, - strand Genetic Position: Chr10, 48.04 cM, cytoband C-D1
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Alliance: |
Elk3tm1.2Ics page
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Delayed retinal angiogenesis during early postnatal stages in Elk3tm1.2Ics/Elk3tm1.2Ics mice
Show the 3 phenotype image(s) involving this allele.
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Germline Transmission: |
Earliest citation of germline transmission:
J:221521
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
129S2/SvPas
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A loxP site was inserted upstream of exon 1. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted downstream of exon 1. Flp-mediated recombination removed the selection cassette. Cre-mediated recombination removed exon 1.
(J:221521)
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Generation of the Elk3tm1.1Ics and Elk3tm1.2Ics alleles |
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Elk3 Mutation: |
20 strains or lines available
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Original: |
J:221521 Weinl C, et al., Elk3 deficiency causes transient impairment in post-natal retinal vascular development and formation of tortuous arteries in adult murine retinae. PLoS One. 2014;9(9):e107048 |
All: |
1 reference(s) |
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