Gskiptm1.1Ekn
Targeted Allele Detail
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Symbol: |
Gskiptm1.1Ekn |
Name: |
GSK3B interacting protein; targeted mutation 1.1, Enno Klussmann |
MGI ID: |
MGI:5784740 |
Synonyms: |
Gskipfl, Gskipflx |
Gene: |
Gskip Location: Chr12:105651611-105669317 bp, + strand Genetic Position: Chr12, 55.92 cM
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Alliance: |
Gskiptm1.1Ekn page
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Germline Transmission: |
Earliest citation of germline transmission:
J:228948
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Parent Cell Line: |
E14.1 (ES Cell)
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Strain of Origin: |
129P2/OlaHsd
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Allele Type: |
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Targeted (Conditional ready, No functional change) |
Mutation: |
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Insertion
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Mutation details: A loxP site was inserted upstream of exon 2. An FRT-flanked neomycin resistance cassette with a 5' loxP site was inserted upstream of exon 3. Flp-mediated recombination removed the selection cassette and left exon 2 floxed.
(J:228948)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Gskip Mutation: |
18 strains or lines available
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Original: |
J:228948 Deak VA, et al., The A-kinase Anchoring Protein GSKIP Regulates GSK3beta Activity and Controls Palatal Shelf Fusion in Mice. J Biol Chem. 2016 Jan 8;291(2):681-90 |
All: |
1 reference(s) |
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