Hcfc1^tm1Lwh
Targeted Allele Detail

Summary

• Symbol: Hcfc1^tm1Lwh
• Name: host cell factor C1; targeted mutation 1, Winship Herr
• MGI ID: MGI:5787629
• Synonyms: Hcfc1^lox
• Gene: Hcfc1 Location: ChrX:72986398-73009963 bp, - strand Genetic Position: ChrX, 37.52 cM, cytoband C1
• Alliance: Hcfc1^tm1Lwh page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:231596
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: C57BL/6

Mutation description

• Allele Type: Targeted (Conditional ready, No functional change)
• Mutation: Insertion
• Mutation details: A loxP site was inserted into intron 1 and an FRT site flanked neomycin resistance cassette and a second loxP site into intron 3. This creates a conditional-ready allele with exons 2 and 3 floxed. (J:231596)

Expression

In Mice Carrying this Mutation:	159 assay results
In Structures Affected by this Mutation:	2 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Hcfc1 Mutation: 8 strains or lines available

References

• Original: J:231596 Minocha S, et al., Compensatory embryonic response to allele-specific inactivation of the murine X-linked gene Hcfc1. Dev Biol. 2016 Apr 1;412(1):1-17
• All: 2 reference(s)