Dip2a^em#aYwz
Endonuclease-mediated Allele Detail

Summary

• Symbol: Dip2a^em#aYwz
• Name: disco interacting protein 2 homolog A; endonuclease-mediated mutation #a, Yaowu Zheng
• MGI ID: MGI:5787957
• Synonyms: Dip2a^delta65kb, Dip2a^em#Ywz
• Gene: Dip2a Location: Chr10:76098581-76181194 bp, - strand Genetic Position: Chr10, 38.76 cM
• Alliance: Dip2a^em#aYwz page

Mutation origin

• Strain of Origin: (C57BL/6 x DBA/2)F1 x C57BL/6J

Mutation description

• Allele Type: Endonuclease-mediated (Not Specified)
• Mutations: Insertion, Intragenic deletion
• Mutation details: CRISPR/Cas9 technology replaced 65 kb downstream of exon 1 with an FRT-flanked neomycin resistance cassette with a 3' loxP site. Founders 3 (64,901 bp), 5 (64,918 bp) and 13 (64,918 bp) transmitted germline. (J:232970)

Expression

In Mice Carrying this Mutation:

62 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Dip2a Mutation: 71 strains or lines available

References

• Original: J:232970 Zhang L, et al., Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9. PLoS One. 2015;10(3):e0120396
• All: 5 reference(s)