Dip2aem#bYwz
Endonuclease-mediated Allele Detail
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Symbol: |
Dip2aem#bYwz |
Name: |
disco interacting protein 2 homolog A; endonuclease-mediated mutation #b, Yaowu Zheng |
MGI ID: |
MGI:5787959 |
Synonyms: |
Dip2aLacZ |
Gene: |
Dip2a Location: Chr10:76098581-76181194 bp, - strand Genetic Position: Chr10, 38.76 cM
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Alliance: |
Dip2aem#bYwz page
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Strain of Origin: |
(C57BL/6 x DBA/2)F1 x C57BL/6J
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Allele Type: |
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Endonuclease-mediated (Reporter) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: CRISPR/Cas9 technology inserted between the 5' UTR and the exon 1 coding sequence a lacZ reporter gene with a nuclear localization sequence, a polyadenylation sequence and an FRT-flanked neomycin resistance cassette. Clones 4 (13 bp deletion), 6 (6 bp deletion), 11 (162 bp deletion), 12 (26 bp deletion), 14 (no deletion) and 17 (7 bp deletion) were generated. Clones 5 and 11 (represented by #) are positive for lacZ insertion.
(J:232970)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Dip2a Mutation: |
71 strains or lines available
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Original: |
J:232970 Zhang L, et al., Large genomic fragment deletions and insertions in mouse using CRISPR/Cas9. PLoS One. 2015;10(3):e0120396 |
All: |
3 reference(s) |
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