Agbl1^em1Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Agbl1^em1Zfa
• Name: ATP/GTP binding protein-like 1; endonuclease-mediated mutation 1, Zusen Fan
• MGI ID: MGI:5787965
• Gene: Agbl1 Location: Chr7:75879635-76774446 bp, + strand Genetic Position: Chr7, 43.87 cM
• Alliance: Agbl1^em1Zfa page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mediated mutagenesis created a 17 bp deletion in exon 8. (J:231311)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agbl1 Mutation: 63 strains or lines available

References

• Original: J:231311 Xia P, et al., Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016 Apr;17(4):369-78
• All: 2 reference(s)