Agbl2^em1Zfa
Endonuclease-mediated Allele Detail

Summary

• Symbol: Agbl2^em1Zfa
• Name: ATP/GTP binding protein-like 2; endonuclease-mediated mutation 1, Zusen Fan
• MGI ID: MGI:5787967
• Gene: Agbl2 Location: Chr2:90613071-90664781 bp, + strand Genetic Position: Chr2, 50.37 cM
• Alliance: Agbl2^em1Zfa page

Mutation origin

• Strain of Origin: Not Specified

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• CRISPR/Cas9 mediated mutagenesis created a 2 bp deletion in exon 7. (J:231311)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Agbl2 Mutation: 66 strains or lines available

References

• Original: J:231311 Xia P, et al., Glutamylation of the DNA sensor cGAS regulates its binding and synthase activity in antiviral immunity. Nat Immunol. 2016 Apr;17(4):369-78
• All: 2 reference(s)