Jpt1^em1(IMPC)J
Endonuclease-mediated Allele Detail

Summary

• Symbol: Jpt1^em1(IMPC)J
• Name: Jupiter microtubule associated homolog 1; endonuclease-mediated mutation 1, Jackson
• MGI ID: MGI:5788505
• Synonyms: Jpt1^em1J
• Gene: Jpt1 Location: Chr11:115388179-115405213 bp, - strand Genetic Position: Chr11, 80.84 cM
• Alliance: Jpt1^em1(IMPC)J page
• IMPC: Jpt1 gene page

Mutation origin

• Strain of Origin: C57BL/6NJ
• Project Collection: IMPC

Mutation description

• Allele Type: Endonuclease-mediated (Null/knockout)
• Mutation: Intragenic deletion
• Mutation details: This allele from project Hn1-7890J-M7394 was generated at The Jackson Laboratory by injecting Cas9 RNA and 4 guide sequences CTGAATCCGTGACTTTAACA, GGCGATCCTTGTTAAAGTCA, ATCGTAAACCCACTGATGGA and GCAGATGGATAAAGCACTGT, which resulted in a 500 bp deletion beginning at Chromosome 11 negative strand position 115,503,346 bp, TGTTGGTACCCTGACCCTCC, and ending after GCGATCCTTGTTAAAGTCAC at 115,502,847 bp (GRCm38/mm10). This mutation deletes exon 2 and 357 bp of flanking intronic sequence including the splice acceptor and donor, and is predicted to cause a change of amino acid sequence after residue 19 and early truncation 3 amino acids later. (J:188991)
• Inheritance: Not Specified

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 1 strain available Cell Lines: 0 lines available
• Carrying any Jpt1 Mutation: 44 strains or lines available

References

• Original: J:188991 The Jackson Laboratory, Alleles produced for the KOMP project by The Jackson Laboratory. MGI Direct Data Submission. 2012
• All: 3 reference(s)