Snap91tm1.1Tmar
Targeted Allele Detail
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Symbol: |
Snap91tm1.1Tmar |
Name: |
synaptosomal-associated protein 91; targeted mutation 1.1, Tanja Maritzen |
MGI ID: |
MGI:5788722 |
Synonyms: |
AP180- |
Gene: |
Snap91 Location: Chr9:86647976-86762707 bp, - strand Genetic Position: Chr9, 46.58 cM, cytoband E3.2
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Alliance: |
Snap91tm1.1Tmar page
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Germline Transmission: |
Earliest citation of germline transmission:
J:228428
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
(C57BL/6NTac x 129S6/SvEvTac)F1
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Allele Type: |
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Targeted (Null/knockout) |
Mutations: |
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Insertion, Intragenic deletion
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Mutation details: A floxed neomycin resistance cassette was inserted in front of exon 3 and an additional loxP site after exon 6. Mice were mated with Ella-Cre Deleter mice to remove the neomycin resistance cassette as well as exons 3 to 6, leaving behind a single loxP site between exon 2 and 7. Western blot analysis confirmed absence of protein expression in brain lysates from adult homozygous mutant mice.
(J:228428)
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View phenotypes and curated references for all genotypes (concatenated display).
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Snap91 Mutation: |
52 strains or lines available
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Original: |
J:228428 Koo SJ, et al., Vesicular Synaptobrevin/VAMP2 Levels Guarded by AP180 Control Efficient Neurotransmission. Neuron. 2015 Oct 21;88(2):330-44 |
All: |
5 reference(s) |
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