Ston1^tm1.1Tmar
Targeted Allele Detail

Summary

• Symbol: Ston1^tm1.1Tmar
• Name: stonin 1; targeted mutation 1.1, Tanja Maritzen
• MGI ID: MGI:5788726
• Synonyms: Stonin1^-
• Gene: Ston1 Location: Chr17:88905043-88955293 bp, + strand Genetic Position: Chr17, 58.1 cM, cytoband E5
• Alliance: Ston1^tm1.1Tmar page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:227201
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• Mutation details: Replacement of the first coding exon, which comprises most of the protein-coding sequence, by a floxed neomycin-resistance cassette. The resulting chimeric males were mated with Ella-Cre deletermice to remove the neomycin-resistance cassette. (J:227201)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ston1 Mutation: 49 strains or lines available

References

• Original: J:227201 Feutlinske F, et al., Stonin1 mediates endocytosis of the proteoglycan NG2 and regulates focal adhesion dynamics and cell motility. Nat Commun. 2015;6:8535
• All: 1 reference(s)