Ticam1^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Ticam1^M2Btlr
• Name: TIR domain containing adaptor molecule 1; mutation 2, Bruce Beutler
• MGI ID: MGI:5789548
• Synonyms: Yue
• Gene: Ticam1 Location: Chr17:56576462-56583767 bp, - strand Genetic Position: Chr17, 29.24 cM
• Alliance: Ticam1^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to C transition at base pair 56,271,339 (v38) on chromosome 17, or base pair 5,429 in the GenBank genomic region NC_000083 encoding the Ticam1 gene. The mutation corresponds to residue 953 in the mRNA sequence NM_174989 within exon 2 of 2 total exons. The mutation results in an isoleucine (I) to threonine (T) substitution at position 252 (I252T) in the protein. (J:234240)
• Inheritance: Dominant

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Ticam1 Mutation: 54 strains or lines available

References

• Original: J:234240 Sun L, et al., Mutagenetix entry for Yue. MGI Direct Data Submission. 2016
• All: 1 reference(s)