Naip5^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Naip5^m2Btlr
• Name: NLR family, apoptosis inhibitory protein 5; mutation 2, Bruce Beutler
• MGI ID: MGI:5789559
• Synonyms: inwood3
• Gene: Naip5 Location: Chr13:100348247-100382831 bp, - strand Genetic Position: Chr13, 53.05 cM, cytoband D1-D3
• Alliance: Naip5^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced C to T transition at base pair 100,221,903 (v38) on chromosome 13, or base pair 32,869 in the GenBank genomic region NC_000079 for the Naip5 gene. The mutation corresponds to residue 3,037 in the mRNA sequence NM_010870 within exon 9 of 14 total exons. The mutation results in substitution of glutamine (Q) 942 for a premature stop codon (Q942*) in the protein. (J:234248)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Naip5 Mutation: 103 strains or lines available

References

• Original: J:234248 Shi H, et al., Mutagenetix entry for inwood3. MGI Direct Data Submission. 2016
• All: 1 reference(s)