Adamts20^m6Btlr
Chemically induced Allele Detail

Summary

• Symbol: Adamts20^m6Btlr
• Name: ADAM metallopeptidase with thrombospondin type 1 motif 20; mutation 6, Bruce Beutler
• MGI ID: MGI:5789560
• Synonyms: nidoking
• Gene: Adamts20 Location: Chr15:94166177-94329966 bp, - strand Genetic Position: Chr15, 48.2 cM
• Alliance: Adamts20^m6Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced G to A transition at base pair 94,403,445 (v38) on chromosome 15, or base pair 61,983 in the GenBank genomic region NC_000081. The mutation corresponds to residue 458 in the mRNA sequence NM_177431 (isoform 1) within exon 2 of 39 total exons and residue 458 in the mRNA sequence NM_00164785 (isoform 2) within exon 2 of 28 total exons. The mutated nucleotide is indicated in red. The mutation results in an arginine (R) to histidine (H) substitution at position 66 (R66H) in both protein variants. (J:234249)
• Inheritance: Recessive

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Adamts20 Mutation: 93 strains or lines available

References

• Original: J:234249 Reyna C, et al., Mutagenetix entry for nidoking. MGI Direct Data Submission. 2016
• All: 1 reference(s)