Pappa2^M2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Pappa2^M2Btlr
• Name: pappalysin 2; mutation 2, Bruce Beutler
• MGI ID: MGI:5789591
• Synonyms: Lilliputian2
• Gene: Pappa2 Location: Chr1:158539297-158788019 bp, - strand Genetic Position: Chr1, 68.49 cM
• Alliance: Pappa2^M2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced T to A transversion at base pair 158,834,918 (v38) on chromosome 1, or base pair 145,606 in the GenBank genomic region NC_000067. The mutation corresponds to residue 3,486 in the mRNA sequence NM_001085376 in exon 10 of 22 total exons. The mutation results in substitution of tyrosine 1,162 to a premature stop codon (Y1162*) in the protein. (J:234256)
• Inheritance: Semidominant

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Pappa2 Mutation: 88 strains or lines available

References

• Original: J:234256 Turer E, et al., Mutagenetix entry for Lilliputian2. MGI Direct Data Submission. 2016
• All: 1 reference(s)