Slc26a4^m1Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slc26a4^m1Btlr
• Name: solute carrier family 26, member 4; mutation 1, Bruce Beutler
• MGI ID: MGI:5789595
• Synonyms: discobolus
• Gene: Slc26a4 Location: Chr12:31569826-31609968 bp, - strand Genetic Position: Chr12, 13.53 cM, cytoband B1
• Alliance: Slc26a4^m1Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 31,540,533 (v38) on chromosome 12, corresponding to base pair 20,105 in the GenBank genomic region NC_000078. The mutation corresponds to residue 1,335 in the NM_011867 mRNA sequence in exon 9 of 21 total exons. The mutation results in substitution of lysine 374 to a premature stop codon (K374*) in the protein. (J:234260)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slc26a4 Mutation: 39 strains or lines available

References

• Original: J:234260 SoRelle J, et al., Mutagenetix entry for discobolus. MGI Direct Data Submission. 2016
• All: 1 reference(s)