Slfn2^m2Btlr
Chemically induced Allele Detail

Summary

• Symbol: Slfn2^m2Btlr
• Name: schlafen 2; mutation 2, Bruce Beutler
• MGI ID: MGI:5789597
• Synonyms: elektra2
• Gene: Slfn2 Location: Chr11:82955938-82961504 bp, + strand Genetic Position: Chr11, 50.3 cM
• Alliance: Slfn2^m2Btlr page

Mutation origin

• Strain of Origin: C57BL/6J
• Project Collection: Beutler Mutagenetix

Mutation description

• Allele Type: Chemically induced (ENU) (Not Specified)
• Mutation: Single point mutation
• Mutation details: ENU-induced A to T transversion at base pair 83,069,564 (v38) on chromosome 11, or base pair 4,453 in the GenBank genomic region NC_000077 for the Slfn2 gene. The mutation corresponds to residue 550 in the mRNA sequence NM_0011408 within exon 2 of 2 total exons. The mutation results in a histidine (H) to leucine (L) substitution at position 123 (H123L) in the protein. (J:234262)
• Inheritance: Recessive

Expression

In Structures Affected by this Mutation:

1 anatomical structure(s)

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Slfn2 Mutation: 14 strains or lines available

References

• Original: J:234262 Choi JH, et al., Mutagenetix entry for elektra2. MGI Direct Data Submission. 2016
• All: 1 reference(s)